Archives

Resisting resistance

  • 18 June 2025
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New peptide champion against drug-resistant cells have entered the battle According to the Australian Cancer Council Federation, at least 2 in 3 Australians will be diagnosed with a type of skin cancer in their lifetime, with a higher risk for men to develop non-melanoma and melanoma skin cancers, compared to women. It was also reported […]

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Structural Insights into CYP450 enzymes

  • 18 June 2025
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Understanding how novel protein tools can make unique cyclic peptides Enzymes are proteins that exist in all living things to accelerate (catalyse) chemical reactions, thus speeding up complex biological processes. Enzymes are involved in a wide variety of biological functions, including digesting food or making copies of DNA. There are many enzymes in nature; specific […]

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Bridging Peptides with RNA

  • 18 June 2025
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Harnessing the flexibility of native chemical ligation to overcome the barriers of traditional therapies Native chemical ligation (NCL) is a remarkable technique widely utilized by peptide chemists to construct large, and increasingly complex peptides and miniature proteins, such as insulin, by fusing two medium-sized peptides. Developed at Scripps Research (USA) just 30 years ago, it […]

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How Butterfly Peas Became the Ultimate Cyclotide Factory

  • 18 June 2025
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Unveiling the evolutionary mystery behind the bioprocessing of cyclotides in plants The butterfly pea legume (Clitoria ternatea) is native to South America and tropical regions of Asia and was introduced to Queensland, Australia in 1991. The legume is best known for its decorative flower with brilliant blue petals. When used as a tea it infuses […]

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Protecting our Australian ground dweller, the Ninu (Greater Bilby)

  • 16 June 2025
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Extracting DNA from Ninu scat to save an iconic marsupial from extinction Australia is home to about two-thirds of the world’s known extant species of marsupials, including Tasmanian devils and quolls (dasyurids or carnivorous marsupials), kangaroos, koalas, and wombats (diprotodonts or herbivores), and bilbies and bandicoots (permelemorphs). Marsupials are an iconic group of animals due […]

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Getting selective with cyclic peptides. Hitting the right target

  • 16 August 2024
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A peptide library is a little like a regular book library. The peptide library has a number of amino acids or books all lined up in a specifically ordered system. We know and understand each book, and we can then make changes and easily see what effect those changes have. These libraries are useful for […]

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Fighting off extinction. Finding cures from within.

  • 16 August 2024
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Australia is home to some unique and wacky wildlife. From our one-of-a-kind platypus to the famous cuddly koala, special features and adaptations to our vast land result in species not found anywhere else in the world. Sadly, a number of our national treasures are already extinct in the wild, and the Tasmanian Devil (Sarcophilus harrisii) […]

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Judging a beer by its bottle. More accurate gluten testing of fermented products offers new hope for Coeliac disease

  • 16 August 2024
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Gluten is the general name for the structural proteins naturally found in wheat, barley and rye. These proteins are sometimes difficult to digest and for those with Coeliac disease (CD), incomplete digestion of gluten triggers an immune-based response in the gut where the body begins attacking itself. The resulting inflammation can lead to numerous symptoms […]

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Pain in the ants. Ant venom a key to unlocking chronic pain.

  • 16 August 2024
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If you’ve had the unfortunate experience of being bitten by a Green Ant (Rhytidoponera metallica) in Australia, you’ll understand the long-lasting pain and irritation inflicted by such a tiny creature. The majority of ant species produce venom and some have characteristic and exceptionally painful stings. The bullet ant (Paraponera clavata) of tropical Central and South […]

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Mapping the entire bilby genome

  • 3 July 2024
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On the back of the Nature family publication, Extant and extinct bilby genomes combined with Indigenous knowledge improve conservation of a unique Australian marsupial | Nature Ecology & Evolution, CIPPS CI’s Carolyn Hogg and Katherine Belov, have received a large amount of media attention.  Read the news article published in The Conversation on 1 July […]

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