Journal Articles

NT*-HRV3CP: An Optimized Construct of Human Rhinovirus 14 3C Protease for High-Yield Expression and Fast Affinity-Tag Cleavage. Journal of Biotechnology (2021) 325, 145-151.

Genetic Encoding of N6-(((Trimethylsilyl)Methoxy)Carbonyl)-l-Lysine for NMR Studies of Protein-Protein and Protein-Ligand Interactions. Journal of the American Chemical Society (2021) 143, 1133-1143.

Potent Trivalent Inhibitors of Thrombin through Hybridization of Salivary Sulfopeptides from Hematophagous Arthropods. Angewandte Chemie International Edition (2021) 60, 5348-5356.

Potency Boost of a Mycobacterium Tuberculosis Dihydrofolate Reductase Inhibitor by Multienzyme F 420 H 2 -Dependent Reduction. Proceedings of the National Academy of Sciences (2021) 118

Late-Stage Hydrocarbon Conjugation and Cyclisation in Synthetic Peptides and Proteins. ChemBioChem (2021) 22, 1784-1789.

Tentacle Morphological Variation Coincides with Differential Expression of Toxins in Sea Anemones. Toxins (2021) 13, 452.

Application of Mass Spectrometry-Based Proteomics to Barley Research. Journal of Agricultural and Food Chemistry (2021)

Cyclic Gomesin, a Stable Redesigned Spider Peptide Able to Enter Cancer Cells. Biochimica et Biophysica Acta (BBA) - Biomembranes (2021) 1863, 183480.

Protein Extraction Protocols for Optimal Proteome Measurement and Arginine Kinase Quantitation from Cricket Acheta Domesticus for Food Safety Assessment. Food Chemistry (2021) 348, 129110.

Proteome and Nutritional Shifts Observed in Hordein Double-Mutant Barley Lines. Frontiers in Plant Science (2021) 12

Quantitative Mass Spectrometry-Based Analysis of Proteins Related to Cattle and Their Products – Focus on Cows’ Milk Beta-Casein Proteoforms. Methods (2021) 186, 112-118.

Late-Stage Modification of Peptides and Proteins at Cysteine with Diaryliodonium Salts. Chemical Science (2021) 12, 14159-14166.

Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates. Cell Chemical Biology (2021) 28, 26-33.e8.

Tuning the Anti-Angiogenic Effect of the P15 Peptide Using Cyclic Trypsin Inhibitor Scaffolds. ACS Chemical Biology (2021) 16, 829-837.

De Novo Macrocyclic Peptides for Inhibiting, Stabilizing, and Probing the Function of the Retromer Endosomal Trafficking Complex. Science Advances (2021) 7

How Can We Improve Peptide Drug Discovery? Learning from the Past. Expert Opinion on Drug Discovery (2021) 16, 1399-1402.

The Evolution and Engineering of Enzyme Activity through Tuning Conformational Landscapes. Protein Engineering, Design and Selection (2021) 34

In Planta Discovery and Chemical Synthesis of Bracelet Cystine Knot Peptides from Rinorea Bengalensis. Journal of Natural Products (2021) 84, 395-407.

Cyclic Peptides as T-Type Calcium Channel Blockers: Characterization and Molecular Mapping of the Binding Site. ACS Pharmacology & Translational Science (2021) 4, 1379-1389.

Synthesis and Evaluation of Peptidic Thrombin Inhibitors Bearing Acid-Stable Sulfotyrosine Analogues. Chemical Communications (2021) 57, 10923-10926.

Total Synthesis of the Spider-Venom Peptide Hi1a. Organic Letters (2021) 23, 8375-8379.

Melanocortin 1 Receptor Agonists Based on a Bivalent, Bicyclic Peptide Framework. Journal of Medicinal Chemistry (2021) 64, 9906-9915.

Perennial Ryegrass Contains Gluten-Like Proteins That Could Contaminate Cereal Crops. Frontiers in Nutrition (2021) 8

Communication Breakdown: Dissecting the COM Interfaces between the Subunits of Nonribosomal Peptide Synthetases. ACS Catalysis (2021) 11, 10802-10813.

Potent Cyclic Peptide Inhibitors of FXIIa Discovered by mRNA Display with Genetic Code Reprogramming. Journal of Medicinal Chemistry (2021) 64, 7853-7876.

Acid-Sensing Ion Channels: Expression and Function in Resident and Infiltrating Immune Cells in the Central Nervous System. Frontiers in Cellular Neuroscience (2021) 15

Substrate Dynamics Contribute to Enzymatic Specificity in Human and Bacterial Methionine Adenosyltransferases. JACS Au (2021) 1, 2349-2360.

Versatile Naphthalimide Tetrazines for Fluorogenic Bioorthogonal Labelling. RSC Chemical Biology (2021) 2, 1491-1498.

Synthetic Protein Conjugate Vaccines Provide Protection against Mycobacterium Tuberculosis in Mice. Proceedings of the National Academy of Sciences (2021) 118

Solid-Phase Synthesis of Coralmycin A/Epi-Coralmycin A and Desmethoxycoralmycin A. Organic & Biomolecular Chemistry (2021) 19 (28), 6291-6300.

Importance of the Cyclic Cystine Knot Structural Motif for Immunosuppressive Effects of Cyclotides. ACS Chemical Biology (2021) 16, 2373-2386.

A Chiral Lanthanide Tag for Stable and Rigid Attachment to Single Cysteine Residues in Proteins for NMR, EPR and Time-Resolved Luminescence Studies. Chemistry - A European Journal (2021) 27, 13009-13023.

Connecting Hydrophobic Surfaces in Cyclic Peptides Increases Membrane Permeability. Angewandte Chemie International Edition (2021) 60, 8385-8390.

Computational and Functional Mapping of Human and Rat α6β4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs. Journal of Medicinal Chemistry (2021) 64, 1685-1700.

Enabling Efficient Folding and High-Resolution Crystallographic Analysis of Bracelet Cyclotides. Molecules (2021) 26, 5554.

Structures of a Non-Ribosomal Peptide Synthetase Condensation Domain Suggest the Basis of Substrate Selectivity. Nature Communications (2021) 12

Pharmacological Inhibition of the Voltage-Gated Sodium Channel NaV1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome. ACS Pharmacology & Translational Science (2021) 4, 1362-1378.

Rapid One-Pot Iterative Diselenide-Selenoester Ligation Using a Novel Coumarin-Based Photolabile Protecting Group. Chemical Science (2021) 12, 10014-10021.

Understanding the Early Stages of Peptide Formation during the Biosynthesis of Teicoplanin and Related Glycopeptide Antibiotics. The FEBS Journal (2020) 288, 507-529.

Mechanistic Insights on How to Avoid and Harness Cyanine Photoconversion. ACS Central Science (2021) 7, 1095-1098.

Comparison of a Short Linear Antimicrobial Peptide with Its Disulfide-Cyclized and Cyclotide-Grafted Variants against Clinically Relevant Pathogens. Microorganisms (2021) 9, 1249.

Fortified Coiled Coils: Enhancing Mechanical Stability with Lactam or Metal Staples. Angewandte Chemie International Edition (2020) 60, 232-236.

Structural and Functional Characterization of a Putative de Novo Gene in Drosophila. Nature Communications (2021) 12

Chemical Probes Reveal the Timing of Early Chlorination in Vancomycin Biosynthesis. Chemical Communications (2021) 57, 2293-2296.

Synthesis of the C1-C27 Fragment of Stambomycin D Validates Modular Polyketide Synthase-Based Stereochemical Assignments. Organic Letters (2021) 23, 7439-7444.

A Bimodal Fluorescence-Raman Probe for Cellular Imaging. Cells (2021) 10, 1699.

Strategies for Organelle Targeting of Fluorescent Probes. Organic & Biomolecular Chemistry (2021) 19, 9339-9357.

An Electrochemical Approach to Designer Peptide α-Amides Inspired by α-Amidating Monooxygenase Enzymes. Journal of the American Chemical Society (2021) 143, 11811-11819.

An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human β-Factor XIIa in a Cyclotide Scaffold. Journal of the American Chemical Society (2021) 143, 18481-18489.

Taking the Myc out of Cancer: Toward Therapeutic Strategies to Directly Inhibit c-Myc. Molecular Cancer (2021) 20

Synthesis of 13C/19F/2H Labeled Indoles for Use as Tryptophan Precursors for Protein NMR Spectroscopy. Organic & Biomolecular Chemistry (2021) 19, 5133-5147.

Development of Novel Frog-skin Peptide Scaffolds with Selectivity towards Melanocortin Receptor Subtypes. Peptide Science (2020) 113

Phosphoserine for the Generation of Lanthanide-Binding Sites on Proteins for Paramagnetic Nuclear Magnetic Resonance Spectroscopy. Magnetic Resonance (2021) 2, 1-13.

Macromolecular Optical Sensor Arrays. ACS Applied Polymer Materials (2021) 3, 506-530.

A Versatile Fluorescent Sensor Array for Platinum Anticancer Drug Detection in Biological Fluids. ACS Sensors (2021) 6, 1261-1269.

Antimicrobial and Anticancer Properties of Synthetic Peptides Derived from the Wasp Parachartergus Fraternus. ChemBioChem (2021) 22, 1415-1423.

Discovery of the Pseudomonas Polyyne Protegencin by a Phylogeny-Guided Study of Polyyne Biosynthetic Gene Cluster Diversity. mBio (2021) 12

Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds That Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain. Journal of Medicinal Chemistry (2021) 64, 9042-9055.

Designed β-Hairpins Inhibit LDH5 Oligomerization and Enzymatic Activity. Journal of Medicinal Chemistry (2021) 64, 3767-3779.

Multipurpose Peptides: The Venoms of Amazonian Stinging Ants Contain Anthelmintic Ponericins with Diverse Predatory and Defensive Activities. Biochemical Pharmacology (2021) 192, 114693.

Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display. ACS Central Science (2021) 7, 1001-1008.

Proteome Analysis and Epitope Mapping in a Commercial Reduced-Gluten Wheat Product. Frontiers in Nutrition (2021) 8

Through-Space Scalar 19F-19F Couplings between Fluorinated Noncanonical Amino Acids for the Detection of Specific Contacts in Proteins. Journal of the American Chemical Society (2021) 143, 19587-19598.

BET-Family Bromodomains Can Recognize Diacetylated Sequences from Transcription Factors Using a Conserved Mechanism. Biochemistry (2021) 60, 648-662.

Staphylococcus Aureus Entanglement in Self-Assembling β-Peptide Nanofibres Decorated with Vancomycin. Nanoscale Advances (2021) 3, 2607-2616.

Antibiotic-Chemoattractants Enhance Neutrophil Clearance of Staphylococcus Aureus. Nature Communications (2021) 12

Koala Cathelicidin PhciCath5 Has Antimicrobial Activity, Including against Chlamydia Pecorum. PLOS ONE (2021) 16, e0249658.

Annotation of Immune Genes in the Extinct Thylacine (Thylacinus Cynocephalus). Immunogenetics (2021) 73, 263-275.

A Reference Genome for the Critically Endangered Woylie, Bettongia Penicillata Ogilbyi. Gigabyte (2021) 2021, 1-15.

Small Cyclic Sodium Channel Inhibitors. Biochemical Pharmacology (2021) 183, 114291.

Converting Peptides into Drugs Targeting Intracellular Protein-Protein Interactions. Drug Discovery Today (2021) 26, 1521-1531.

Angler Peptides: Macrocyclic Conjugates Inhibit P53:MDM2/X Interactions and Activate Apoptosis in Cancer Cells. ACS Chemical Biology (2021) 16, 414-428.

Venom Composition of the Endoparasitoid Wasp Cotesia Flavipes (Hymenoptera: Braconidae) and Functional Characterization of a Major Venom Peptide. Toxicon (2021) 202, 1-12.

Cyclotides from Brazilian Palicourea Sessilis and Their Effects on Human Lymphocytes. Journal of Natural Products (2021) 84, 81-90.

Effects of Backbone Cyclization on the Pharmacokinetics and Drug Efficiency of the Orally Active Analgesic Conotoxin CVc1.1. Medicine in Drug Discovery (2021) 10, 100087.

Chemical Synthesis of Phosphorylated Insulin-like Growth Factor Binding Protein 2. Journal of the American Chemical Society (2021) 143, 5336-5342.

Preparation, Validation and Use of a Vasoactive Tryptophan-Derived Hydroperoxide and Relevant Control Compounds. Nature Protocols (2021) 16, 3382-3418.

Therapeutic Inhibition of Acid-Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury. Circulation (2021) 144, 947-960.

Asparaginyl Ligases: New Enzymes for the Protein Engineer’s Toolbox. ChemBioChem (2021) 22, 2079-2086.

Enzymatic C-Terminal Protein Engineering with Amines. Journal of the American Chemical Society (2021) 143, 19498-19504.

Improved Asparaginyl-Ligase-Catalyzed Transpeptidation via Selective Nucleophile Quenching. Angewandte Chemie International Edition (2020) 60, 4004-4008.

A Pain-Causing and Paralytic Ant Venom Glycopeptide. iScience (2021) 24, 103175.

Expanding the Substrate Scope of Nitrating Cytochrome P450 TxtE by Active Site Engineering of a Reductase Fusion. ChemBioChem (2021)

Docking Domain-Mediated Subunit Interactions in Natural Product Megasynth(et)Ases. Journal of Industrial Microbiology and Biotechnology (2021) 48

Ancestral Sequence Reconstruction for Protein Engineers. Current Opinion in Structural Biology (2021) 69, 131-141.

A Comprehensive Phylogenetic Analysis of the Serpin Superfamily. Molecular Biology and Evolution (2021) 38, 2915-2929.

Increased Valency Improves Inhibitory Activity of Peptides Targeting Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9). ChemBioChem (2021) 22, 2154-2160.

Bioactive Cyclization Optimizes the Affinity of a Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Peptide Inhibitor. Journal of Medicinal Chemistry (2021) 64, 2523-2533.

Engineered EGF-A Peptides with Improved Affinity for Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9). ACS Chemical Biology (2021) 16, 429-439.

The Emerging Landscape of Peptide-Based Inhibitors of PCSK9. Atherosclerosis (2021) 330, 52-60.

Evaluation of Efficient Non-Reducing Enzymatic and Chemical Ligation Strategies for Complex Disulfide-Rich Peptides. Bioconjugate Chemistry (2021) 32, 2407-2419.

Challenges of Short Substrate Analogues as SARS-CoV-2 Main Protease Inhibitors. Bioorganic & Medicinal Chemistry Letters (2021) 50, 128333.

Sunflower Trypsin Inhibitor-1 (SFTI-1): Sowing Seeds in the Fields of Chemistry and Biology. Angewandte Chemie International Edition (2020) 60, 8050-8071.

Linking Molecular Evolution to Molecular Grafting. Journal of Biological Chemistry (2021) 296, 100425.

Glycosylation Regulates N-Terminal Proteolysis and Activity of the Chemokine CCL14. ACS Chemical Biology (2021) 16, 973-981.

Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors. Journal of Medicinal Chemistry (2021) 64, 5620-5631.

Elucidating the Roles of Fenton Reactants in Drug-Treated Cells by Using a Selective Rhodamine-Thiophenol Fluorogenic Sensor. Analysis & Sensing (2021) 1, 90-94.

Cell-Free Synthesis of Selenoproteins in High Yield and Purity for Selective Protein Tagging. ChemBioChem (2021) 22, 1480-1486.

Interactions of Globular and Ribbon [?4E]GID with α4β2 Neuronal Nicotinic Acetylcholine Receptor. Marine Drugs (2021) 19, 482.

Yeast-Based Bioproduction of Disulfide-Rich Peptides and Their Cyclization via Asparaginyl Endopeptidases. Nature Protocols (2021) 16, 1740-1760.

An Integrated Molecular Grafting Approach for the Design of Keap1-Targeted Peptide Inhibitors. ACS Chemical Biology (2021) 16, 1276-1287.

Rational Design of Potent Peptide Inhibitors of the PD-1:PD-L1 Interaction for Cancer Immunotherapy. Journal of the American Chemical Society (2021) 143, 18536-18547.

Understanding the Glycopeptide Antibiotic Crosslinking Cascade: In Vitro Approaches Reveal the Details of a Complex Biosynthesis Pathway. ChemBioChem (2020) 22, 43-51.

Molecular Basis for Control of Antibiotic Production by a Bacterial Hormone. Nature (2021) 590, 463-467.

Platypus and Echidna Genomes Reveal Mammalian Biology and Evolution. Nature (2021) 592, 756-762.

A Colorimetric Sensor Array for the Classification of Biologically Relevant Tri-, Di- and Mono-Phosphates. Organic & Biomolecular Chemistry (2021) 19 (5), 1017-1021.

Rational Domestication of a Plant-Based Recombinant Expression System Expands Its Biosynthetic Range. Journal of Experimental Botany (2022)

A Peptide Toxin in Ant Venom Mimics Vertebrate EGF-like Hormones to Cause Long-Lasting Hypersensitivity in Mammals. Proceedings of the National Academy of Sciences (2022) 119, e2112630119.

Investigations into the Membrane Activity of Arenicin Antimicrobial Peptide AA139. Biochimica et Biophysica Acta (BBA) - General Subjects (2022) 1866, 130156.

Multitarget Nociceptor Sensitization by a Promiscuous Peptide from the Venom of the King Baboon Spider. Proceedings of the National Academy of Sciences (2022) 119, e2110932119.

The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade Is Highly Sensitive to Oxidative Damage. Frontiers in Chemistry (2022) 10

Chemical Synthesis and Semisynthesis of Lipidated Proteins. Angewandte Chemie International Edition (2022) 61

Synthetic Vaccines Targeting Mincle through Conjugation of Trehalose Dibehenate. Chemical Communications (2022) 58, 6890-6893.

Beyond Vancomycin: Recent Advances in the Modification, Reengineering, Production and Discovery of Improved Glycopeptide Antibiotics to Tackle Multidrug-Resistant Bacteria. Current Opinion in Biotechnology (2022) 77, 102767.

Potent Bactericidal Antimycobacterials Targeting the Chaperone ClpC1 Based on the Depsipeptide Natural Products Ecumicin and Ohmyungsamycin A. Journal of Medicinal Chemistry (2022)

The Tarantula Toxin ω-Avsp1a Specifically Inhibits Human CaV3.1 and CaV3.3 via the Extracellular S3-S4 Loop of the Domain 1 Voltage-Sensor. Biomedicines (2022) 10, 1066.

Diene Incorporation by a Dehydratase Domain Variant in Modular Polyketide Synthases. Nature Chemical Biology (2022) 18, 1410-1416.

Protocols for Measuring the Stability and Cytotoxicity of Cyclotides. Methods in Enzymology (2022) 19-40.

Sex-Specific Expression of Pheromones and Other Signals in Gravid Starfish. BMC Biology (2022) 20

The Present and the Future of Protein Biosensor Engineering. Current Opinion in Structural Biology (2022) 75, 102424.

Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction. Angewandte Chemie International Edition (2022) 61

Phage Display-Based Discovery of Cyclic Peptides against the Broad Spectrum Bacterial Anti-Virulence Target CsrA. European Journal of Medicinal Chemistry (2022) 231, 114148.

DEER Experiments Reveal Fundamental Differences between Calmodulin Complexes with IQ and MARCKS Peptides in Solution. Structure (2022) 30, 813-827.e5.

Selenium Is the Chalcogen of Choice for Selective Reporting of Thioredoxin Reductase Activity. Chem (2022) 8, 1175-1177.

Antiviral Cyclic Peptides Targeting the Main Protease of SARS-CoV-2. Chemical Science (2022)

Short-Range ENDOR Distance Measurements between Gd(iii) and Trifluoromethyl Labels in Proteins. Physical Chemistry Chemical Physics (2022)

The Mosaic Oat Genome Gives Insights into a Uniquely Healthy Cereal Crop. Nature (2022) 606, 113-119.

A Fluorescent Sensor for Quantitative Super-Resolution Imaging of Amyloid Fibril Assembly. Angewandte Chemie International Edition (2022) 61

Expressed Protein Selenoester Ligation. Angewandte Chemie International Edition (2022) 61

Cystine Knot Peptides with Tuneable Activity and Mechanism. Angewandte Chemie (2022) 134

Replacing Commercial 6-Phosphofructokinase in an Online Pyrophosphate Detection Assay. ChemBioChem (2022) 23

Electrochemistry for the Chemoselective Modification of Peptides and Proteins. Journal of the American Chemical Society (2021) 144, 23-41.

Organoarsenic Probes to Study Proteins by NMR Spectroscopy. Chemical Communications (2022) 58, 701-704.

Site-Selective Photocatalytic Functionalization of Peptides and Proteins at Selenocysteine. Nature Communications (2022) 13

Mutagenesis of Bracelet Cyclotide Hyen D Reveals Functionally and Structurally Critical Residues for Membrane Binding and Cytotoxicity. Journal of Biological Chemistry (2022) 298, 101822.

Generation of Oligonucleotide Conjugates via One-Pot Diselenide-Selenoester Ligation-Deselenization/Alkylation. Chemical Science (2022) 13, 410-420.

Antimicrobial Peptides Provide Wider Coverage for Targeting Drug-resistant Bacterial Pathogens. Peptide Science (2021) 114

Modified Horseshoe Crab Peptides Target and Kill Bacteria inside Host Cells. Cellular and Molecular Life Sciences (2021) 79

Resonant Dielectric Metagratings for Response Intensified Optical Sensing. Advanced Functional Materials (2021) 32, 2103143.

Swapping N-Terminal Regions among Tick Evasins Reveals Cooperative Interactions Influencing Chemokine Binding and Selectivity. Journal of Biological Chemistry (2022) 298, 102382.

Mucosal TLR2-Activating Protein-Based Vaccination Induces Potent Pulmonary Immunity and Protection against SARS-CoV-2 in Mice. Nature Communications (2022) 13

Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L. Journal of Medicinal Chemistry (2021) 65, 2956-2970.

Venoms for All Occasions: The Functional Toxin Profiles of Different Anatomical Regions in Sea Anemones Are Related to Their Ecological Function. Molecular Ecology (2021) 31, 866-883.

Proteome Phenotypes Discriminate the Growing Location and Malting Traits in Field-Grown Barley. Journal of Agricultural and Food Chemistry (2022) 70, 10680-10691.

Intramolecular Interactions Enhance the Potency of Gallinamide A Analogues against Trypanosoma Cruzi. Journal of Medicinal Chemistry (2022)

Peptide Macrocyclisation via Late-Stage Reductive Amination. Organic & Biomolecular Chemistry (2022) 20, 6250-6256.

Accurate de Novo Design of Membrane-Traversing Macrocycles. Cell (2022)

Comparison of Protein Extraction Protocols and Allergen Mapping from Black Soldier Fly Hermetia Illucens. Journal of Proteomics (2022) 269, 104724.

Structure-Guided Engineering of Tick Evasins for Targeting Chemokines in Inflammatory Diseases. Proceedings of the National Academy of Sciences (2022) 119

Comparative Analysis of Cyclotide-Producing Plant Cell Suspensions Presents Opportunities for Cyclotide Plant Molecular Farming. Phytochemistry (2022) 195, 113053.

A Designed Cyclic Analogue of Gomesin Has Potent Activity against Staphylococcus Aureus Biofilms. Journal of Antimicrobial Chemotherapy (2022) 77, 3256-3264.

The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel NaV1.8 to Enhance Activation. Frontiers in Pharmacology (2022) 12

Landscaping Macrocyclic Peptides: Stapling HDM2-Binding Peptides for Helicity, Protein Affinity, Proteolytic Stability and Cell Uptake. RSC Chemical Biology (2022) 3, 895-904.

Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides. Angewandte Chemie International Edition (2022) 61

The Acyclotide Ribe 31 from Rinorea Bengalensis Has Selective Cytotoxicity and Potent Insecticidal Properties in Drosophila. Journal of Biological Chemistry (2022) 102413

Mutagenesis of Cyclotide Cter 27 Exemplifies a Robust Folding Strategy for Bracelet Cyclotides. Peptide Science (2022)

An N-Capping Asparagine-Lysine-Proline (NKP) Motif Contributes to a Hybrid Flexible/Stable Multifunctional Peptide Scaffold. Chemical Science (2022) 13, 9410-9424.

The Deadly Toxin Arsenal of the Tree-Dwelling Australian Funnel-Web Spiders. International Journal of Molecular Sciences (2022) 23, 13077.

A PH-Based Single-Sensor Array for Discriminating Metal Ions in Water. Chemistry - An Asian Journal (2022)

A Fluorescent Sensor Array for the Discrimination of Nucleotide Phosphates. Analysis & Sensing (2022)

Cancer-Related Micropeptides Encoded by NcRNAs: Promising Drug Targets and Prognostic Biomarkers. Cancer Letters (2022) 547, 215723.

Evaluation of Protein Extraction Methods for In-Depth Proteome Analysis of Narrow-Leafed Lupin (Lupinus Angustifolius) Seeds. Food Chemistry (2022) 367, 130722.

Evaluation of the Major Seed Storage Proteins, the Conglutins, Across Genetically Diverse Narrow-Leafed Lupin Varieties. Frontiers in Nutrition (2022) 9

Engineering the Cyclization Loop of MCoTI-II Generates Targeted Cyclotides That Potently Inhibit Factor XIIa. Journal of Medicinal Chemistry (2022) 65, 15698-15709.

Main Protease Mutants of SARS-CoV-2 Variants Remain Susceptible to Nirmatrelvir. Bioorganic & Medicinal Chemistry Letters (2022) 62, 128629.

CIPPS, an Australian Centre for Peptide and Protein Research, Goes Live! Peptides (2022) 155, 170835.

Modifying a Hydroxyl Patch in Glucagon-like Peptide 1 Produces Biased Agonists with Unique Signaling Profiles. Journal of Medicinal Chemistry (2022) 65, 11759-11775.

Late-Stage Functionalization with Cysteine Staples Generates Potent and Selective Melanocortin Receptor-1 Agonists. Journal of Medicinal Chemistry (2022) 65, 12956-12969.

Umpolung Strategies for the Functionalization of Peptides and Proteins. Chemical Science (2022)

Computational Design and Experimental Characterisation of a Stable Human Heparanase Variant. RSC Chemical Biology (2022) 3, 341-349.

The Structural Conformation of the Tachykinin Domain Drives the Anti-tumoural Activity of an Octopus Peptide in Melanoma BRAF V600E. British Journal of Pharmacology (2022)

Mitochondrial Succinate Dehydrogenase (SDHA) Function Is Essential for Sperm Motility and Male Fertility. iScience (2022) 105573

Helical Structure in Cyclic Peptides: Effect of N-Methyl Amides versus Esters. Chemical Communications (2022) 58, 12475-12478.

Towards a Generic Prototyping Approach for Therapeutically-Relevant Peptides and Proteins in a Cell-Free Translation System. Nature Communications (2022) 13

Neurotoxic and Cytotoxic Peptides Underlie the Painful Stings of the Tree Nettle Urtica Ferox. Journal of Biological Chemistry (2022) 298, 102218.

?O-Conotoxin GeXIVA Isomers Modulate N-type Calcium (Ca V 2.2) Channels and Inwardly-rectifying Potassium (GIRK) Channels via GABA B Receptor Activation. Journal of Neurochemistry (2021)

Improving Stability Enhances In Vivo Efficacy of a PCSK9 Inhibitory Peptide. Journal of the American Chemical Society (2022) 144, 19485-19498.

Cytochrome P450Blt Enables Versatile Peptide Cyclisation to Generate Histidine- and Tyrosine-Containing Crosslinked Tripeptide Building Blocks. Angewandte Chemie International Edition (2022) 61

Tyrosine-O-Sulfation Is a Widespread Affinity Enhancer among Thrombin Interactors. Biochemical Society Transactions (2022)

Synthesis of Fluorinated Leucines, Valines and Alanines for Use in Protein NMR. Organic & Biomolecular Chemistry (2022) 20, 2424-2432.

Synthesis of Peptide N-Acylpyrroles via Anodically Generated N,O-Acetals. Synthesis (2022)

New Boron-Based Coumarin Fluorophores for Bioimaging Applications. Australian Journal of Chemistry (2022) 75, 716-724.

μ-Conotoxins Targeting the Human Voltage-Gated Sodium Channel Subtype NaV1.7. Toxins (2022) 14, 600.

Site-Selective Generation of Lanthanoid Binding Sites on Proteins Using 4-Fluoro-2,6-Dicyanopyridine. Magnetic Resonance (2022) 3, 169-182.

Paramagnetic Chemical Probes for Studying Biological Macromolecules. Chemical Reviews (2022) 122, 9571-9642.

Composition and Toxicity of Venom Produced by Araneophagous White-Tailed Spiders (Lamponidae: Lampona Sp.). Scientific Reports (2022) 12

Antinociceptive Peptides from Venomous Arthropods. Toxin Reviews (2022) 42, 362-381.

Peptide-Based LDH5 Inhibitors Enter Cancer Cells and Impair Proliferation. Cellular and Molecular Life Sciences (2022) 79

Localising Nuclear Spins by Pseudocontact Shifts from a Single Tagging Site. Magnetic Resonance (2022) 3, 65-76.

Localising Individual Atoms of Tryptophan Side Chains in the Metallo-β-Lactamase IMP-1 by Pseudocontact Shifts from Paramagnetic Lanthanoid Tags at Multiple Sites. Magnetic Resonance (2022) 3, 1-13.

Genome Assembly of the Numbat (Myrmecobius Fasciatus), the Only Termitivorous Marsupial. Gigabyte (2022) 2022, 1-17.

Best Genome Sequencing Strategies for Annotation of Complex Immune Gene Families in Wildlife. GigaScience (2022) 11

Cloning and Expression of Burkholderia Polyyne Biosynthetic Gene Clusters in Paraburkholderia Hosts Provides a Strategy for Biopesticide Development. Microbial Biotechnology (2022) 15, 2547-2561.

Proteotranscriptomics Reveals the Secretory Dynamics of Teratocytes, Regulators of Parasitization by an Endoparasitoid Wasp. Journal of Insect Physiology (2022) 139, 104395.

Site-Specific Incorporation of 7-Fluoro-L-Tryptophan into Proteins by Genetic Encoding to Monitor Ligand Binding by 19F NMR Spectroscopy. ACS Sensors (2022) 7, 44-49.

Enzymatic C-to-C Protein Ligation. Angewandte Chemie (2022) 134

Predicting Antiviral Resistance Mutations in SARS-CoV-2 Main Protease with Computational and Experimental Screening. Biochemistry (2022) 61, 2495-2505.

Adventures on the Routes of Protein Evolution—In Memoriam Dan Salah Tawfik (1955–2021). Journal of Molecular Biology (2022) 434

Structural Analysis of the Complex of Human Transthyretin with 3′,5′-Dichlorophenylanthranilic Acid at 1.5 Å Resolution. Molecules (2022) 27

Genetic Encoding of 7-Aza-l-Tryptophan: Isoelectronic Substitution of a Single CH-Group in a Protein for a Nitrogen Atom for Site-Selective Isotope Labeling. ACS Sensors (2023) 8, 4402-4406.

Molecular Fluorescent Sensors for in Vivo Imaging. Current Opinion in Biotechnology (2023) 83, 102973.

Serum Albumin Binding Knob Domains Engineered within a VH Framework III Bispecific Antibody Format and as Chimeric Peptides. Frontiers in Immunology (2023) 14

From Squid Giant Axon to Automated Patch-Clamp: Electrophysiology in Venom and Antivenom Research. Frontiers in Pharmacology (2023) 14

Two Novel Mosquitocidal Peptides Isolated from the Venom of the Bahia Scarlet Tarantula (Lasiodora Klugi). Toxins (2023) 15, 418.

Suppression of MR1 by Human Cytomegalovirus Inhibits MAIT Cell Activation. Frontiers in Immunology (2023) 14

Genomic, Functional and Structural Analyses Elucidate Evolutionary Innovation within the Sea Anemone 8 Toxin Family. BMC Biology (2023) 21

Molecular Insights into Metabolite Antigen Recognition by Mucosal-Associated Invariant T Cells. Current Opinion in Immunology (2023) 83, 102351.

From Grain to Malt: Tracking Changes of Ultra-Low-Gluten Barley Storage Proteins after Malting. Food Chemistry (2024) 432, 137189.

Proteome Changes Resulting from Malting in Hordein-Reduced Barley Lines. Journal of Agricultural and Food Chemistry (2023) 71, 14079-14091.

Nematicidal Activity of Cyclotides: Toxicity Against Caenorhabditis Elegans. Journal of Natural Products (2023) 86, 1222-1229.

Cross-Linking Mass Spectrometry Discovers, Evaluates, and Corroborates Structures and Protein-Protein Interactions in the Human Cell. Proceedings of the National Academy of Sciences (2023) 120

Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. ACS Chemical Biology (2023)

A Macrocyclic Fluorescent Probe for the Detection of Citrate. Organic & Biomolecular Chemistry (2023) 21, 8548-8553.

Designing Antimicrobial Peptides Using Deep Learning and Molecular Dynamic Simulations. Briefings in Bioinformatics (2023) 24

New Drug Targets and Preclinical Modelling Recommendations for Treating Acute Myocardial Infarction. Heart, Lung and Circulation (2023) 32, 852-869.

Holistic Profiling of the Venom from the Brazilian Wandering Spider Phoneutria Nigriventer by Combining High-Throughput Ion Channel Screens with Venomics. Frontiers in Molecular Biosciences (2023) 10

The Voltage-gated Sodium Channel Na V 1 .7 Underlies Endometriosis-associated Chronic Pelvic Pain. Journal of Neurochemistry (2023)

3D Structure of the Transient Intermediate of the Enzyme-Substrate Complex of Sortase A Reveals How Calcium Binding and Substrate Recognition Cooperate in Substrate Activation. ACS Catalysis (2023) 11610-11624.

Heparan Sulfate Regulates IL-21 Bioavailability and Signal Strength That Control Germinal Center B Cell Selection and Differentiation. Science Immunology (2023) 8

Position-Specific N- and O-Glycosylation of the Reactive Centre Loop Impacts Neutrophil Elastase-Mediated Proteolysis of Corticosteroid-Binding Globulin. Journal of Biological Chemistry (2023) 105519

Engineering Broad-Spectrum Inhibitors of Inflammatory Chemokines from Subclass A3 Tick Evasins. Nature Communications (2023) 14

Genomes of Two Extinct-in-the-Wild Reptiles from Christmas Island Reveal Distinct Evolutionary Histories and Conservation Insights. Molecular Ecology Resources (2023)

Probing Ligand Binding Sites on Large Proteins by Nuclear Magnetic Resonance Spectroscopy of Genetically Encoded Non-Canonical Amino Acids. Journal of Medicinal Chemistry (2023)

The Genome Sequence of the Critically Endangered Kroombit Tinkerfrog (Taudactylus Pleione). F1000Research (2023) 12, 845.

Late-Stage, Stereoretentive, and Site-Selective Modification of Synthetic Peptides by Using Photoredox Catalysis. Chemistry - A European Journal (2023)

Genetic or Pharmacological Ablation of Acid-Sensing Ion Channel 1a (ASIC1a) Is Not Neuroprotective in a Mouse Model of Spinal Cord Injury. Journal of Neurotrauma (2023)

Acute Inhibition of Acid Sensing Ion Channel 1a after Spinal Cord Injury Selectively Affects Excitatory Synaptic Transmission, but Not Intrinsic Membrane Properties, in Deep Dorsal Horn Interneurons. PLOS ONE (2023) 18, e0289053.

Discovery and Optimisation of Conotoxin Vc1.1 and Analogues with Analgesic Properties. Australian Journal of Chemistry (2023) 76, 655-670.

Effect of a Protease-activated Receptor-2 Antagonist (GB88) on Inflammation-related Loss of Alveolar Bone in Periodontal Disease. Journal of Periodontal Research (2023) 58, 544-552.

Discovery and Characterization of Cyclic Peptides Selective for the C-Terminal Bromodomains of BET Family Proteins. Structure (2023) 31, 912-923.e4.

Exploring the Therapeutic Potential of an Antinociceptive and Anti-Inflammatory Peptide from Wasp Venom. Scientific Reports (2023) 13

N-(2-Aminophenyl)-Benzamide Inhibitors of Class I HDAC Enzymes with Antiproliferative and Antifibrotic Activity. Journal of Medicinal Chemistry (2023) 66, 14357-14376.

Metabolic Engineering of the Shikimate Pathway in Amycolatopsis Strains for Optimized Glycopeptide Antibiotic Production. Metabolic Engineering (2023) 78, 84-92.

Venom Composition and Bioactive RF-Amide Peptide Toxins of the Saddleback Caterpillar, Acharia Stimulea (Lepidoptera: Limacodidae). Biochemical Pharmacology (2023) 213, 115598.

Towards Multimodal Cellular Imaging: Optical and X-Ray Fluorescence. Chemical Society Reviews (2023)

Amino Acid Sulfinate Salts as Alkyl Radical Precursors. Organic Letters (2023) 25, 3157-3162.

Utilizing Proteomics to Identify and Optimize Microalgae Strains for High-Quality Dietary Protein: A Review. Critical Reviews in Biotechnology (2023) 1-16.

Nutrition, Allergenicity and Physicochemical Qualities of Food-Grade Protein Extracts from Nannochloropsis Oculata. Food Chemistry (2023) 424, 136459.

Resurrecting Ancestral Antibiotics: Unveiling the Origins of Modern Lipid II Targeting Glycopeptides. Nature Communications (2023) 14

Synthesis and Applications of Mirror-Image Proteins. Nature Reviews Chemistry (2023)

Chemoselective Methionine Labelling of Recombinant Trastuzumab Shows High In Vitro and In Vivo Tumour Targeting. Chemistry - A European Journal (2023) 29

Molecular Probes for Fluorescent Sensing of Metal Ions in Non-Mammalian Organisms. Current Opinion in Chemical Biology (2023) 74, 102311.

Development and Validation of Nerve-Targeted Bacteriochlorin Sensors. Journal of the American Chemical Society (2023) 145, 14276-14287.

Exploring the Selectivity and Engineering Potential of an NRPS Condensation Domain Involved in the Biosynthesis of the Thermophilic Siderophore Fuscachelin. Frontiers in Catalysis (2023) 3

Not Always an Innocent Bystander: The Impact of Stabilised Phosphopantetheine Moieties When Studying Nonribosomal Peptide Biosynthesis. Chemical Communications (2023) 59, 8234-8237.

Exploring the Flexibility of the Glycopeptide Antibiotic Crosslinking Cascade for Extended Peptide Backbones. ChemBioChem (2023) 24

Clp-Targeting BacPROTACs Impair Mycobacterial Proteostasis and Survival. Cell (2023)

Parallelized Gene Cluster Editing Illuminates Mechanisms of Epoxyketone Proteasome Inhibitor Biosynthesis. Nucleic Acids Research (2023) 51, 1488-1499.

Plant-Based Production of an Orally Active Cyclotide for the Treatment of Multiple Sclerosis. Transgenic Research (2023) 32, 121-133.

Pain-Causing Stinging Nettle Toxins Target TMEM233 to Modulate NaV1.7 Function. Nature Communications (2023) 14

Impact of Nano-Titanium Dioxide Extracted from Food Products on Caco-2 Cells Using Three-Phase Digestion Model. Environmental Science: Nano (2023)

The Structural Components of the Azotobacter Vinelandii Iron-Only Nitrogenase, AnfDKG, Form a Protein Complex within the Plant Mitochondrial Matrix. Plant Molecular Biology (2023) 112, 279-291.

Asymmetric Ene-Reduction of α,β-Unsaturated Compounds by F420-Dependent Oxidoreductases A Enzymes from Mycobacterium Smegmatis. Biochemistry (2022) 62, 873-891.

Asymmetric Ene-Reduction by F420-Dependent Oxidoreductases B (FDOR-B) from Mycobacterium Smegmatis. ChemBioChem (2023) 24

Fine-Tuning Electroauxiliary-Mediated Peptide Modifications Using Second-Generation Electroactive Amino Acids. Organic Letters (2023) 25, 3633-3638.

Tunable Electrochemical Peptide Modifications: Unlocking New Levels of Orthogonality for Side-Chain Functionalization. Angewandte Chemie (2023) 135

Photochemical Mechanisms of Fluorophores Employed in Single-Molecule Localization Microscopy. Angewandte Chemie (2022) 135

Squaramides for Colorimetric and Fluorescent Anion Sensing. Organic & Biomolecular Chemistry (2023) 21, 3226-3234.

Analytical Methods for Allergen Control in Food Processing. Foods (2023) 12, 1439.

Unravelling the Mystery of COVID-19 Pathogenesis: Spike Protein and Cu Can Synergize to Trigger ROS Production. Chemistry - A European Journal (2023)

Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure-Activity Relationships to Therapeutic Applications. International Journal of Molecular Sciences (2023) 24, 5893.

Electrochemical Modification of Polypeptides at Selenocysteine. Angewandte Chemie International Edition (2023) 62

Exploiting Chemical Protein Synthesis to Study the Role of Tyrosine Sulfation on Anticoagulants from Hematophagous Organisms. Accounts of Chemical Research (2023)

Electrostatic Contribution to 19F Chemical Shifts in Fluorotryptophans in Proteins. Biochemistry (2023) 62, 3255-3264.

Ozone-Enabled Fatty Acid Discovery Reveals Unexpected Diversity in the Human Lipidome. Nature Communications (2023) 14

Investigations of Cellular Copper Metabolism in Ovarian Cancer Cells Using a Ratiometric Fluorescent Copper Dye. JBIC Journal of Biological Inorganic Chemistry (2022) 28, 43-55.

Captivity Induces a Sweeping and Sustained Genomic Response in a Starfish. Molecular Ecology (2023) 32, 3541-3556.

Development of Melanocortin 4 Receptor Agonists by Exploiting Animal-Derived Macrocyclic, Disulfide-Rich Peptide Scaffolds. ACS Pharmacology & Translational Science (2023) 6, 1373-1381.

Design and Structural Validation of Peptide-Drug Conjugate Ligands of the Kappa-Opioid Receptor. Nature Communications (2023) 14

Development of a Selective Peptide κ-Opioid Receptor Antagonist by Late-Stage Functionalization with Cysteine Staples. Journal of Medicinal Chemistry (2023) 66, 11843-11854.

Safe Food through Better Labelling; a Robust Method for the Rapid Determination of Caprine and Bovine Milk Allergens. Food Chemistry (2023) 417, 135885.

Bibliometric Review of the Literature on Cone Snail Peptide Toxins from 2000 to 2022. Marine Drugs (2023) 21, 154.

Application of Near-Infrared Spectroscopy and Chemometrics for the Rapid Detection of Insect Protein Adulteration from a Simulated Matrix. Food Control (2024) 159, 110268.

Low Gluten Beers Contain Variable Gluten and Immunogenic Epitope Content. Foods (2023) 12, 3252.

Proteomic Exploration Reveals a Metabolic Rerouting Due to Low Oxygen during Controlled Germination of Malting Barley (Hordeum Vulgare L.). Frontiers in Plant Science (2023) 14

Responsible Nanotechnology for a Sustainable Future. One Earth (2023) 6, 763-766.

Deciphering the Structure and Mechanism of Action of Computer-designed Mastoparan Peptides. The FEBS Journal (2023)

Development of Antiplasmodial Peptide-Drug Conjugates Using a Human Protein-Derived Cell-Penetrating Peptide with Selectivity for Infected Cells. Bioconjugate Chemistry (2023) 34, 1105-1113.

Tasmanian Devil Cathelicidins Exhibit Anticancer Activity against Devil Facial Tumour Disease (DFTD) Cells. Scientific Reports (2023) 13

Adaptive Genetic Management of a Reintroduction Program from Captive Breeding to Metapopulation Management of an Arboreal Marsupial. Diversity (2023) 15, 848.

Immunosuppressive, Antimicrobial and Insecticidal Activities of Inhibitor Cystine Knot Peptides Produced by Teratocytes of the Endoparasitoid Wasp Cotesia Flavipes (Hymenoptera: Braconidae). Insect Science (2022) 30, 1105-1117.

The Predatory Stink Bug Arma Custos (Hemiptera: Pentatomidae) Produces a Complex Proteinaceous Venom to Overcome Caterpillar Prey. Biology (2023) 12, 691.

PROTACs Targeting MLKL Protect Cells from Necroptosis. Journal of Medicinal Chemistry (2023)

Acid-Sensing Ion Channel 1a Blockade Reduces Myocardial Injury in Rodent Models of Myocardial Infarction. European Heart Journal (2023)

Ant Venoms Contain Vertebrate-Selective Pain-Causing Sodium Channel Toxins. Nature Communications (2023) 14

Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium Tuberculosis. Microbiology Spectrum (2023)

Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces Sp. CMB-TU011. Marine Drugs (2023) 21, 487.

The β3-subunit Modulates the Effect of Venom Peptides ProTx-II and OD1 on NaV1.7 Gating. Journal of Cellular Physiology (2023) 238, 1354-1367.

Protease-Activated Receptor 2 Attenuates Doxorubicin-Induced Apoptosis in Colon Cancer Cells. Journal of Cell Communication and Signaling (2023) 17, 1293-1307.

Conventional Solid-State Fermentation Impacts the White Lupin Proteome Reducing the Abundance of Allergenic Peptides. Food Chemistry (2023) 426, 136622.

Second Generation Synthesis of the Anti-Infective Natural Product Gallinamide A. Tetrahedron (2023) 133445

A Broad-Spectrum Macrocyclic Peptide Inhibitor of the SARS-CoV-2 Spike Protein. Proceedings of the National Academy of Sciences (2023) 120

Evaluation of Peptide Ligation Strategies for the Synthesis of the Bivalent Acid-Sensing Ion Channel Inhibitor Hi1a. Organic Letters (2023) 25, 4439-4444.

Changes in Potency and Subtype Selectivity of Bivalent NaV Toxins Are Knot-Specific. Bioconjugate Chemistry (2023)

Native and Engineered Cyclic Disulfide-Rich Peptides as Drug Leads. Molecules (2023) 28, 3189.

Selective Removal of Sulfate from Water by Precipitation with a Rigid Bis-amidinium Compound. Angewandte Chemie International Edition (2023) 62

The Plant Defensin Ppdef1 Is a Novel Topical Treatment for Onychomycosis. Journal of Fungi (2023) 9, 1111.

Improved Spectral Resolution of [13C,1H]-HSQC Spectra of Aromatic Amino Acid Residues in Proteins Produced by Cell-Free Synthesis from Inexpensive 13C-Labelled Precursors. Journal of Biomolecular NMR (2023) 77, 183-190.

Cell-Free Synthesis of Proteins with Selectively 13C-Labelled Methyl Groups from Inexpensive Precursors. Magnetic Resonance (2023) 4, 187-197.

An Improved Method for the Detection of Myeloperoxidase Chlorinating Activity in Biological Systems Using the Redox Probe Hydroethidine. Free Radical Biology and Medicine (2023) 195, 23-35.

Cell-Penetrating Peptide-Bismuth Bicycles. Angewandte Chemie International Edition (2024) 63

Proteome of Urticating Setae of Ochrogaster Lunifer, a Processionary Caterpillar of Medical and Veterinary Importance, Including Primary Structures of Putative Toxins. PROTEOMICS (2023)

Horizontal Gene Transfer Underlies the Painful Stings of Asp Caterpillars (Lepidoptera: Megalopygidae). Proceedings of the National Academy of Sciences (2023) 120

The Circular Bacteriocin Enterocin NKR-5-3B Has an Improved Stability Profile over Nisin. Peptides (2023) 167, 171049.

Hydrogel Oxygen Reservoirs Increase Functional Integration of Neural Stem Cell Grafts by Meeting Metabolic Demands. Nature Communications (2023) 14

Complex Inhibitory Mechanism of Glycomimetics with Heparanase. Biochemistry (2023) 62, 2202-2215.

Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages. Journal of Innate Immunity (2023) 468-484.

Computational Design of α-conotoxins to Target Specific Nicotinic Acetylcholine Receptor Subtypes. Chemistry - A European Journal (2023)

Structure-Activity Relationships of Alanine Scan Mutants αO-Conotoxins GeXIVA[1,2] and GeXIVA[1,4]. Journal of Medicinal Chemistry (2023) 66, 10092-10107.

Structural Diversity, Biosynthesis, and Biological Functions of Lipopeptides from Streptomyces. Natural Product Reports (2023)

P450-Mediated Dehydrotyrosine Formation during WS9326 Biosynthesis Proceeds via Dehydrogenation of a Specific Acylated Dipeptide Substrate. Acta Pharmaceutica Sinica B (2023) 13, 3561-3574.

Design, Synthesis, and Mechanism of Action of Novel μ-Conotoxin KIIIA Analogues for Inhibition of the Voltage-Gated Sodium Channel Nav1.7. Journal of Biological Chemistry (2023) 299, 103068.

A Chemoenzymatic Approach To Produce a Cyclic Analogue of the Analgesic Drug MVIIA (Ziconotide). Angewandte Chemie (2023) 135

BODIPY-based Fluorescent Indicators for Lipid Droplets. Analysis & Sensing (2023)

Discovery, Characterization, and Engineering of LvIC, an α4/4-Conotoxin That Selectively Blocks Rat α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of Medicinal Chemistry (2023) 66, 2020-2031.

Genomic insights into the critically endangered King Island scrubtit Journal of Heredity (2024)

Characterisation of Defensins across the Marsupial Family Tree. Comparative Immunology (2024) 105207

Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS‐CoV‐2 Main Protease with Antiviral Activity. Chemistry – A European Journal (2024)

(Re)Imagining Purpose: A Framework for Sustainable Nanotechnology Innovation NanoImpact (2024) 100511

Structural Insights into a Side Chain Cross-Linking Biarylitide P450 from RiPP Biosynthesis. ACS Catalysis (2024) 14 812–826.

Enhancing PET Degrading Enzymes: A Combinatory Approach. ChemBioChem (2024)

Improving Plastic Degrading Enzymes via Directed Evolution. Protein Engineering, Design and Selection (2024) 37

Rugged Fitness Landscapes Minimize Promiscuity in the Evolution of Transcriptional Repressors. Cell Systems (2024) 15 374-387

Mononuclear Binding and Catalytic Activity of Europium(III) and Gadolinium(III) at the Active Site of the Model Metalloenzyme Phosphotriesterase Acta Crystallographica Section D Structural Biology (2024) 80 , 289–298

Identification and Characterization of a Bacterial Periplasmic Solute Binding Protein That Binds l-Amino Acid Amides Biochemistry (2024) 63 1322-1334

Structural Basis of Chemokine Recognition by the Class A3Tick Evasin EVA‐ACA1001 Protein Science (2024) 33

Small-Molecule Fluorescent Probes for Binding- and Activity-Based Sensing of Redox-Active Biological Metals Chemical Reviews (2024)

Genomic and Transcriptomic Resources for the Brown Thornbill (Acanthiza Pusilla) to Support the Conservation of a Critically Endangered Subspecies. F1000Research (2024) 13 337

A Reference Genome, Mitochondrial Genome and Associated Transcriptomes for the Critically Endangered Swift Parrot (Lathamus Discolor). F1000Research (2024) 13 251

Supramolecular Control of the Temperature Responsiveness of Fluorescent Macrocyclic Molecular Rotamers. Chemistry – A European Journal (2024)

An Engineered Biarylitide Cross-Linking P450 from RiPP Biosynthesis Generates Alternative Cyclic Peptides. Organic Letters (2024) 26 1828–1833

Antibiotic Skeletal Diversification via Differential Enoylreductase Recruitment and Module Iteration in Trans-Acyltransferase Polyketide Synthases. Journal of the American Chemical Society (2024) 146 6114–6124

Synthetic Ramoplanin Analogues Are Accessible by Effective Incorporation of Arylglycines in Solid-Phase Peptide Synthesis. Chemical Science (2024) 15 195–203

A Coumarin-Based Array for the Discrimination of Amyloids. ACS Sensors (2024)

Integrating Phenotypic and Chemoproteomic Approaches to Identify Covalent Targets of Dietary Electrophiles in Platelets. ACS Central Science (2024)

A Chromosome-Level Genome Assembly for the Dugong (Dugong Dugon). Journal of Heredity, (2024)

Structural Insights into a Side Chain Cross-Linking Biarylitide P450 from RiPP Biosynthesis. ACS Catalysis (2024) 14 812–826

Accessing diverse bicyclic peptide conformations using 1,2,3-TBMB as a linker Organic and Biomolecular Chemistry (2024), Advance Article

Development of stapled NONO-associated peptides reveals unexpected cell permeability and nuclear localisation Journal of Peptide Science (2024), May 30(5):e3562

A change in metal cation switches selectivity of a phospholipid sensor from phosphatidic acid to phosphatidylserine Organic and Biomolecular Chemistry (2024)

Total Synthesis of a Peptide Diatom Sex Pheromone Bearing a Sulfated Aspartic Acid Organic Letters (2024)

Genetic Encoding of Fluoro-l-tryptophans for Site-Specific Detection of Conformational Heterogeneity in Proteins by NMR Spectroscopy Journal of the American Chemical Society (2024), 146,19, 13641-13650

(2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5′-Difluoroleucine in Escherichia coli PpiB: Protein Production, 19F NMR, and Ligand Sensing Enhanced by the γ-Gauche Effect Biochemistry (2024), 63, 11, 1376-1387

Effects of Laccase and Transglutaminase on the Physicochemical and Functional Properties of Hybrid Lupin and Whey Protein Powder Foods (2024), 13, 2090

Research trends in production, separation, and identification of bioactive peptides from fungi – A critical review Journal of Functional Foods (2024), 119, 106343

Characterising the Tasmanian devil (Sarcophilus harrisii) pouch microbiome in lactating and non-lactating females Scientific Reports (2024), 14

Topology in soft and biological matter Physics Reports (2024), 1075, 1–137

Aspartic acid mutagenesis of αO-Conotoxin GeXIVA isomers reveals arginine residues crucial for inhibition of the α9α10 nicotinic acetylcholine receptor International Journal of Biological Macromolecules (2024), 271, 132472

Design, Synthesis, and Structure–Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus-2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors Journal of Medicinal Chemistry 2024, 67, 11, 9587–9598

Repurposing a Plant Peptide Cyclase for Targeted Lysine Acylation Nature Chemistry (2024)

MAIT Cell-MR1 Reactivity Is Highly Conserved across Multiple Divergent Species Journal of Biological Chemistry (2024), 300, 107338

Hi1a Improves Sensorimotor Deficit Following Endothelin-1-Induced Stroke in Rats but Does Not Improve Functional Outcomes Following Filament-Induced Stroke in Mice ACS Pharmacology and Translational Science (2024), 7, 1043–1054

Phylogeny, Envenomation Syndrome, and Membrane Permeabilising Venom Produced by Australia’s Electric Caterpillar Comana Monomorpha Scientific Reports (2024), 14

Structure and Bioactivity of an Insecticidal Trans-Defensin from Assassin Bug Venom Structure (2024)

Protease-Activated Receptor 2: A Promising Therapeutic Target for Women’s Cancers Journal of Pharmacology and Experimental Therapeutics 2024, JPET-MR-2024-002176

Sulfated Bile Acid Is a Host-Derived Ligand for MAIT Cells Science Immunology (2024), 9

Wnt Dose Escalation during the Exit from Pluripotency Identifies Tranilast as a Regulator of Cardiac Mesoderm Developmental Cell (2024), 59, 705-722.e8

Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis Angewandte Chemie International Edition (2024)

Mouse Mucosal-Associated Invariant T Cell Receptor Recognition of MR1 Presenting the Vitamin B Metabolite, 5-(2-Oxopropylideneamino)-6-d-Ribitylaminouracil Journal of Biological Chemistry (2024), 300, 107229

Coat Protein of a Whitefly‐vectored Plant Virus as a Delivery System to Target Whitefly Microbial Biotechnology (2024), 17

De Novo Annotation of the Wheat Pan-Genome Reveals Complexity and Diversity within the Hexaploid Wheat Pan-Transcriptome bioRxiv (2024)

LC-MS/MS Reveals Hordeins Are Enriched in Brewers’ Spent Grain Journal of the American Society for Mass Spectrometry (2024) 35 (3), 409-412

Advancing Sustainable Malting Practices: Aquaporins as Potential Breeding Targets for Improved Water Uptake during Controlled Germination of Barley (Hordeum vulgare L.) Journal of Agricultural and Food Chemistry (2024), 72 (17), 10149-10161

Tyrosine Sulfation Modulates the Binding Affinity of Chemokine-Targeting Nanobodies ACS Chemical Biology (2024)

Increasing the Soluble Expression and Whole-Cell Activity of the Plastic-Degrading Enzyme MHETase through Consensus Design Biochemistry (2024)

Ancestral Reconstruction of Polyethylene Terephthalate Degrading Cutinases Reveals a Rugged and Unexplored Sequence-Fitness Landscape bioRxiv (2024)

Development of supramolecular anticoagulants with on-demand reversibility Nature Biotechnology (2024)

Isolation and Characterization of Insecticidal Cyclotides from Viola Communis Journal of Natural Products (2024)

NaV1.7 targeted fluorescence imaging agents for nerve identification during intraoperative procedures bioRxiv (2024)

Peptide Toxins That Target Vertebrate Voltage-Gated Sodium Channels Underly the Painful Stings of Harvester Ants Journal of Biological Chemistry (2024), 300, 105577

Molecular Dynamics Simulations Support a Preference of Cyclotide Kalata B1 for Phosphatidylethanolamine Phospholipids Biochimica et Biophysica Acta (BBA) - Biomembranes (2024), 1866, 184268

Delivery to, and Reactivation of, the P53 Pathway in Cancer Cells Using a Grafted Cyclotide Conjugated with a Cell-Penetrating Peptide Journal of Medicinal Chemistry (2024), 67, 1197–1208

The Pearl Jubilee of Microcin J25: Thirty Years of Research on an Exceptional Lasso Peptide Natural Product Reports (2024), 41, 469–511

Tertiary Amide Bond Formation by an Engineered Asparaginyl Ligase Chemical Science (2024), 15, 5248–5255

Chemical Synthesis of Grafted Cyclotides Using a “Plug and Play” Approach. RSC Chemical Biology (2024), 5, 567–571

Conotoxins Targeting Voltage-Gated Sodium Ion Channels. Pharmacological Reviews (2024), PHARMREV-AR-2023-000923

Scanning Mutagenesis Identifies Residues That Improve the Long-Term Stability and Insecticidal Activity of Cyclotide Kalata B1 Journal of Biological Chemistry (2024), 300, 105682

Nucleation of a Key Beta-Turn Promotes Cyclotide Oxidative Folding Journal of Biological Chemistry (2024), 300, 107125

Sortase‐Catalyzed Protein Domain Inversion Angewandte Chemie International Edition (2024), 63

Structure and Activity of Reconstructed Pseudo‐Ancestral Cyclotides. ChemMedChem (2024)

Proximity Labelling Confirms the Involvement of Papain-Like Cysteine Proteases and Chaperones in Cyclotide Biosynthesis Plant Molecular Biology Reporter (2024)

Display Technologies for Expanding the Pharmaceutical Applications of Cyclotides Israel Journal of Chemistry (2024)

Seasonal Tissue-Specific Gene Expression in Wild Crown-of-Thorns Starfish Reveals Reproductive and Stress-Related Transcriptional Systems. PLOS Biology (2024), 22, e3002620